The Sceptre Story & Team
OUR MISSON
Revolutionize orthopedic care by eradicating infections with innovative technology, improving patient outcomes, and enhancing healthcare efficiency.
THE SCEPTRE STORY
2021
INCEPTION OF SCEPTRE & PATENT APPLICATIONS
During his time in orthopedic surgery residency at Dartmouth, Dr. Tim McManus began to notice a troubling and significant lack of effective treatment solutions that are specifically designed to address orthopedic implant-associated infections. This observation led him to further explore the root causes of these infections, ultimately leading him to conduct several basic science studies and file patent applications.
2023
2024
BASIC SCIENCE STUDIES - THE “SABER SERIES”
The SABER (Study on Agitation for Biofilm Eradication & Reduction) studies focus on addressing the challenging issue of biofilm-associated infections on orthopedic implants. Conducted at Dartmouth under the guidance of Dr. George O’Toole, these studies evaluate the efficacy of using a combination of mechanical brushing, sonic technology, and radiofrequency to disrupt and eradicate biofilms. Biofilms, which are bacterial colonies that form fortified layers on surfaces, pose significant treatment challenges due to their resistance to antibiotics and other treatment measures. The SABER studies have shown promising results in significantly reducing biofilm burden on various metal alloys commonly used in orthopedic implants, demonstrating that these methods can be more effective than traditional techniques. The results have been showcased at premier academic orthopedic society meetings, such as the American Academy of Orthopedics (AAOS), the American Association of Hip & Knee Surgeons (AAHKS), and the University of Colorado Orthopaedic Research Symposium.
Accepted to:
INCORPORATION OF SCEPTRE MEDICAL
Dr. Tim McManus and Ryan McManus officially incorporate Sceptre Medical Co as a Delaware C-Corp. This pivotal step marks a major milestone in our journey, solidifying our commitment to growth, innovation, and excellence in the medical field. As a newly established corporation, we are excited to explore new opportunities and drive forward groundbreaking advancements that will shape the future of healthcare.
UNIVERSITY OF MICHIGAN BUSINESS CHALLENGE - 2ND PLACE
Over a rigorous six-month competition spanning four rounds and competing against over 100 innovative startups, Co-founder & CEO Ryan McManus, along with his Michigan Ross classmates Maya Ambady and Graham Beck, proudly secured second place in the University of Michigan Business Challenge, winning $7,500 in prize money. Sceptre was recognized as one of the top innovative companies in the competition, marking a significant milestone that will support bringing Sceptre to market. We’re thrilled to have been among the top innovators, but for us, second place is just the start. Our real victory will be delivering first-rate solutions for our patients, because when it comes to their care, there’s no room for second best.
SCEPTRE PARTNERS WITH PROTOTYPING FIRM -VITATEK
Sceptre is delighted to announce its partnership with Vitatek, a top Development & Manufacturing firm based in the heart of "Medical Alley." This collaboration aims to fast-track the development of the Sceptre Brush, leveraging Vitatek's exceptional prototyping and manufacturing expertise. Together, we are committed to advancing Sceptre's dedication to providing cutting-edge solutions in the surgical field.
SCEPTRE PARTNERS WITH ENGINEERING FIRM - PSOUP
Sceptre is delighted to announce its partnership with Psoup, a premier medical device Design & Engineering firm based in Minnesota. This collaboration aims to fast-track the development of the Sceptre Brush, leveraging Psoup’s world-class expertise and team of former Microsoft, Philips Sonicare, and Lockheed Martin engineers, with project experience including DePuy/J&J’s KINCISE Surgical Automated System. Together, we are committed to advancing Sceptre’s dedication to providing cutting-edge solutions in the surgical field.
THE TEAM
Ryan McManus
CHIEF EXECUTIVE OFFICER
Tim McManus, MD
CHIEF MEDICAL OFFICER
Tim is an orthopaedic surgeon at Summit Orthopedics in Minnesota. He completed his sports medicine fellowship at Steadman Hawkins Clinic in Denver and his residency training at Dartmouth. He received his B.A. in history from Dartmouth College. Prior to residency, he completed his post-baccalaureate studies at Harvard Extension School, worked as a Business Analyst at Medtronic, and attended medical school at The Ohio State University College of Medicine. He is also a co-founder of Jennus Innovation, an early-stage startup accelerator.
George O’Toole, PhD
SENIOR SCIENCE ADVISOR
George is one of the world’s leading biofilm experts and is The Elmer R. Pfefferkorn, Ph.D. Professor of Microbiology & Immunology at Geisel School of Medicine at Dartmouth. He received his Ph.D. from the University of Wisconsin-Madison and performed postdoctoral studies at Harvard Medical School as a Damon-Runyon and a Hood Fellow with Roberto Kolter, Ph.D. His honors include the NSF Career Award, Pew Scholar in the Biomedical Sciences, election as a fellow of AAAS and American Academy of Microbiology, and serving as Editor in Chief for the Journal of Bacteriology.
Ryan graduated with distinction from the University of Michigan’s Ross School of Business, focusing on healthcare and entrepreneurship. Prior to receiving his MBA, he served as the Director of Sales & Marketing at MVP, a startup focused on providing robotic training solutions for athletic and tactical training. At MVP, Ryan built & led MVP’s go-to-market, sales, and marketing strategies. He also co-founded Jennus Innovation, an early-stage startup accelerator. Ryan received his B.A. in history from Dartmouth College.
